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Miyamoto Y
Pharmacol Res
inhibits HDAC4 and HDAC5 in skeletal muscle and the heart without affecting HDAC3 activity
InChiKey: BKLJDIJJOOQUFG-UHFFFAOYSA-N
Manning Fox JE
Trimethylamine N-oxide - CAS# 1184-78-7 60140 Miyamoto YTrimethylamine N oxide, CAS No. 1184 78 7, is a gut microbe dependent metabolite of dietary choline and other trimethylamine containing nutrients. Trimethylamine N oxide induces inflammation by activating the ROS NLRP3 inflammasome. Trimethylamine N oxide also accelerates fibroblast myofibroblast differentiation and induces cardiac fibrosis by activating the TGF smad2 signaling pathway. Product information CAS Number: 1184 78 7 Molecular Weight: 75.
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